As the health problems of the elderly gradually appear as they grow older, all along,multivitaminThey are all one of the popular gifts for elders during the New Year. However, there are thousands of multivitamins, and there are very few products with more rigorous research data. However, in recent years, with the assistance of research method updates and technological progress, Under this circumstance, large-scale special nutritional intervention studies on the efficacy of multivitamins are gradually being carried out.
In 2023, there will be a large-scale special nutritional intervention related to multivitaminsstudiesThe results of the thesis were published in the high-scoring journal in the field of nutrition: "The American Journal of Clinical Nutrition" (The American Journal of Clinical Nutrition). This paper mainly hopes to explore the effect of comprehensive vitamins on the memory of the elderly. The research data comes from the COSMOS trial (a 3-year 2×2 randomized double-blind study, which aims to explore the effects of cocoa flavanols and comprehensive vitamins on the elderly. health effects), a total of 3562 elders who participated in the study were randomly assigned to the "combined vitamin group" or "placebo group". For three years, use ModRey, ModBent, and Flanker tests to quantify and measure the memory ability of the elderly related to hippocampal function, among which ModRey test is the main measurement data.
After the analysis of Linear mixed-effects models, the research team found that in the first year of follow-up, the elders who took the comprehensive vitamin group performed better on the ModRey test, and the vocabulary of short-term memory increased from an average of 7.1 to 7.81, while The elderly who took the placebo only increased from 7.21 words to 7.65, and this effect persisted even in the third year of follow-up (as shown in the figure below); if compared with the decline in vocabulary memory caused by normal aging, taking The effect of comprehensive vitamins is equivalent to delaying memory decline for about 3.1 years! In addition, this effect is more obvious in the elderly with cardiovascular disease!
In summary, although compared with the test data of more than 10,000 people in drug-related research on the market, the number of people in this research seems to be relatively small, but in the field of special nutrition intervention, such standardized research can be achieved, and more than 3,000 people were tested. Those who are already very rare! No wonder it can be published in high-scoring journals. The author believes that although many factors still need to be considered in the research (such as: conflict of interest, selection criteria of main data, etc.), the measurement data in this paper still affirms the certain effect of comprehensive vitamins on delaying memory decline. Under the condition that there is not much doubt about sex, and memory is an important factor to maintain the quality of life, the author believes that comprehensive vitamins can be regarded as one of the good health maintenance programs for the elderly (for other maintenance programs, please refer to the pastArticle 1,Article 2); As for which formula of multivitamins to choose, the author still recommends that you should seek an evaluation from a relevant professional physician before purchasing.
〈The author is former Attending Physician in National Taiwan University Hospital, and Master of Science from National Taiwan University〉