US National Poisons Program (National Toxicology Program, NTP), by the U.S. Department of Health and Human Services (United States Department of Health and Human Services, HHS) in an interdepartmental program that collaborates across sectors: the National Institute of Environmental Health Sciences (National Institute of Environmental Health Sciences, NIEHS), the National Cancer Institute (National Cancer Institute, NCI), the National Institute for Occupational Safety and Health (National Institute for Occupational Safety and Health, NIOSH) and so on; this project can be said to be the culmination of poison research in the United States. Through cross-unit cooperation, it can make a complete and comprehensive assessment of the growing poison, and provide information as an important reference for the revision of health-related policies. Regarding cancer, in addition to the professional evaluation conducted by specialized agencies in major countries, there are also international organizations to discuss and analyze carcinogens: the International Agency for Research on Cancer (IARC), the author has in the past made a classification for its classification.Introduction.
In this update of the list of human carcinogens, NTP has added a total of 8 human carcinogens, of which 1 is added to "Known To Be Human Carcinogens", and "Very Likely to Be Carcinogens" (Known To Be Human Carcinogens) is added. To Be Human Carcinogens) added 7 new species and added them toupdate resultPublished in the heavyweight medical journal JAMA Network in 2022.
First of all, the addition of "Known To Be Human Carcinogens" is very common in civilized society:Chronic Helicobacter pylori infection, Such infections are common among ethnic groups with lower socioeconomic status, and the main route of infection is human-to-human transmission, and it may also be transmitted through contaminated drinking water.
The seven new substances in "Known To Be Human Carcinogens" are:Antimony Trioxideand6 Haloacetic Acids (HAAs).
Antimony trioxide is mainly used as a flame retardant, and can be used in pigments, ceramics, cement, glass products, etc. in industry. Although there may be occasional exposure in daily life, the dose is low, and it is more likely to be exposed in large quantities. Usually occupational exposure.
The 6 haloacetic acids (HAAs) include: Bromochloroacetic Acid, Bromodichloroacetic Acid, Chlorodibromoacetic Acid, Dibromoacetic Acid, Dichloroacetic Acid, Tribromoacetic Acid. The above six haloacetic acids are all by-products of chlorine-based water disinfectants. For ordinary people, the most likely source of exposure in daily life is drinking water. , there are higher doses of potential exposure due to hygiene requirements, however, with proper activated carbon filtration, these harmful by-products can be effectively removed.
To sum up, in addition to the preliminary understanding of the newly added 8 carcinogens, the author recommends that you review your daily life to see if there are potential sources of exposure, and if so, it is recommended to reduce exposure as much as possible; and for the possibility of chronic infection , you should receive appropriate tests to find out whether you are infected, and professional medical personnel should be invited to give follow-up treatment recommendations based on the test results.
〈The author is former Attending Physician in National Taiwan University Hospital, and Master of Science from National Taiwan University〉
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